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Botanix has both the expertise and equipment to offer wide-ranging support for CO2 extraction projects, both in terms of analysis of extracted products, and further downstream processing and formulation. We can offer the following supporting technologies: Analysis Gas chromatography (GC) and combined GC-MS. High performance liquid chromatography (HPLC-UV; dual wavelength and PDA detectors). Routine analysis: Optical rotation (OR), refractive index (RI), specific gravity (SG), Fourier Transform Infrared Spectroscopy (FT-IR) and moisture analysis. Downstream processing or formulation Molecular distillation Fractional distillation Derivatisation Pilot Spray-drying plant for production of sample powders.




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	Shimadzu HPLC



	LC2010A Image courtesy of Shimadzu

	PerkinElmer GC



	Clarus 500 GC Image courtesy of PerkinElmer


Botanix Ltd has three Shimadzu HPLC instruments, each with dual wavelength UV - visible detectors at the Paddock Wood site, and a further four HPLC instruments at the Eardiston site. HPLC is ideally suited for the analysis and quantification of many natural molecules, and is used routinely at Botanix for quality control and for research and development purposes. Botanix will always perform analysis to support our extraction technologies wherever possible, so that we are able to rapidly determine the success of extraction protocols, and to adjust these accordingly. Our instruments have autosampler capability, allowing for efficient processing and analysis of samples. In addition, we also have a further HPLC instrument used exclusively for research and development activities.

	PerkinElmer GC-MS



		Clarus 500 GCMS Image courtesy of PerkinElmer.

Many natural products (for instance essential oils) consist of small molecules that are easily volatilised, and therefore gas chromatography (GC) is an ideal method of analysis. The components of a particular natural product can be readily and rapidly separated and quantified with GC, and thus our GC capabilities complement the HPLC instruments to allow a very wide scope in analytical capability. We also have a GC linked to a mass spectrometer (GC/MS), which enables us to identify unknown components or to verify the presence of a particular molecule. The new Perkin Elmer instruments are fitted with autosamplers to allow efficient processing of analytical samples.




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